Crystal Structure of Thermus aquaticus Core RNA Polymerase at 3.3 Å Resolution
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چکیده
منابع مشابه
Crystal Structure of Thermus aquaticus Core RNA Polymerase at 3.3 Å Resolution
The X-ray crystal structure of Thermus aquaticus core RNA polymerase reveals a "crab claw"-shaped molecule with a 27 A wide internal channel. Located on the back wall of the channel is a Mg2+ ion required for catalytic activity, which is chelated by an absolutely conserved motif from all bacterial and eukaryotic cellular RNA polymerases. The structure places key functional sites, defined by mut...
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ژورنال
عنوان ژورنال: Cell
سال: 1999
ISSN: 0092-8674
DOI: 10.1016/s0092-8674(00)81515-9